O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate - Names and Identifiers
Name | (1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate
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Synonyms | 6-Boc-3-Cbz-3,6-diazabicyclo[3.2.0]heptane 3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate (1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate 3,6-Diazabicyclo[3.2.0]heptane-3,6-dicarboxylic acid, 6-(1,1-dimethylethyl) 3-(phenylmethyl) ester
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CAS | 370880-79-8
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O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate - Physico-chemical Properties
Molecular Formula | C18H24N2O4
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Molar Mass | 332.39416 |
Density | 1.218±0.06 g/cm3(Predicted) |
Boling Point | 446.5±28.0 °C(Predicted) |
pKa | -0.84±0.20(Predicted) |
Storage Condition | 2-8℃ |
O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate - Upstream Downstream Industry
O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate - Introduction
(1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate, also known as (1R,5S)-(1R,5S)-3-benzene 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
This compound is a colorless to pale yellow solid with a melting point of about 140-145 degrees Celsius. It is stable at room temperature and soluble in some organic solvents, such as chloroform, methanol and dichloromethane.
Use:
This compound has a wide range of applications. It can be used as a pharmaceutical intermediate for the preparation of various pharmaceuticals, such as antibiotics, anticancer drugs, etc. In addition, it can also be used in organic synthesis and chemical industry.
Method:
A common preparation method is by adding a quaternary ammonium salt to 4-cyanobenzeneacetonitrile. In the preparation process, the quaternary ammonium salt is first reacted with cyanobenzeneacetonitrile, and the electrophilic alkyne is generated under the catalysis of alkali. Then the alkyne reacts with the nucleophile, and then through a series of reaction steps, the target product is finally obtained.
Safety Information:
When handling and using this compound, pay attention to safety. It may be irritating to the eyes, skin and respiratory system and may be potentially dangerous to health. Therefore, appropriate personal protective equipment such as laboratory gloves, protective glasses and laboratory suits should be used during operation. In addition, work should be done in a well-ventilated area to avoid inhaling or coming into contact with powders or vapors of the compound. If necessary, it is recommended to consult a chemical professional or refer to the relevant safety data sheet.
Last Update:2024-04-09 20:52:54